发明名称 |
METHODS AND COMPOSITIONS FOR PROGNOSING DETECTING AGE-RELATED MACULAR DEGENERATION |
摘要 |
The invention provides methods and compositions for determining whether a subject is at risk of developing age-related macular degeneration, for example, the wet or neovascular form of age-related macular degeneration. The method involves determining whether the subject has a protective variant and/or a risk variant at a polymorphic site in the RORA gene. A protective or risk variant may be defined by a haplotype in the RORA gene. |
申请公布号 |
WO2010127176(A2) |
申请公布日期 |
2010.11.04 |
申请号 |
WO2010US33052 |
申请日期 |
2010.04.29 |
申请人 |
MASSACHUSETTS EYE AND EAR INFIRMARY;DE ANGELIS, MARGARET, M.;MORRISON, MARGAUX |
发明人 |
DE ANGELIS, MARGARET, M.;MORRISON, MARGAUX |
分类号 |
C12Q1/68;C12N15/12;C40B40/08 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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