发明名称 |
METHOD FOR PRODUCTION OF ORALLY RAPIDLY DISINTEGRATING TABLET COMPRISING IMIDAFENACIN AS ACTIVE INGREDIENT |
摘要 |
The present invention herein provides an imidafenacin-containing orally rapidly disintegrating tablet which is excellent in the photostability. The present invention comprises the steps of: (A) granulating imidafenacin together with starch to thus give a granulated product having an imidafenacin concentration ranging from 0.001 to 3% by mass and a starch concentration ranging from 40 to 99.999% by mass; (B) covering the granulated product prepared in the step (A) with a non-cellulosic coating agent; and (C) blending the granulated product obtained in the preceding step (B) with an excipient and a disintegrating agent and then forming the resulting mixture into a tablet according to the compression molding technique.
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申请公布号 |
EP2246051(A1) |
申请公布日期 |
2010.11.03 |
申请号 |
EP20090705447 |
申请日期 |
2009.01.30 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIZAKI, TOSHIHIRO;AOKI, YOSHINOBU |
分类号 |
A61K31/4164;A61K9/00;A61K9/16;A61K9/20;A61K9/22;A61K9/50;A61K47/32;A61K47/36;A61K47/38;A61P13/10;A61P43/00 |
主分类号 |
A61K31/4164 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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