| 发明名称 |
(Biphenyl) carboxylic acids and derivatives thereof |
| 摘要 |
The present invention relates to compounds having the general formula (I) with the definitions of A, X, R1-R6 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of γ-secretase activity.
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| 申请公布号 |
US7825160(B2) |
申请公布日期 |
2010.11.02 |
| 申请号 |
US20050665760 |
申请日期 |
2005.10.21 |
| 申请人 |
CELLZOME LIMITED |
发明人 |
WILSON FRANCIS;REID ALISON;READER VALERIE;HARRISON RICHARD JOHN;SUNOSE MIHIRO;HERNANDEZ-PERNI REMEDIOS;MAJOR JEREMY;BOUSSARD CYRILLE;SMELT KATHRYN;TAYLOR JESS;LEFORMAL ADELINE;CANSFIELD ANDREW;BURCKHARDT SVENJA |
| 分类号 |
A01N37/10;A01N37/08;A01N53/00;A61K31/19;A61K31/557;C07C61/04;C07C61/16;C07C62/00;C07C63/00;C07C63/33;C07C63/333;C07C65/00 |
主分类号 |
A01N37/10 |
| 代理机构 |
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