发明名称 |
Synthesis of FR901464 and analogs with antitumor activity |
摘要 |
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing.
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申请公布号 |
US7825267(B2) |
申请公布日期 |
2010.11.02 |
申请号 |
US20070852278 |
申请日期 |
2007.09.08 |
申请人 |
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
KOIDE KAZUNORI;ALBERT BRIAN J.;SIVARAMAKRISHNAN ANANTHAPADMANABHAN |
分类号 |
C07D315/00 |
主分类号 |
C07D315/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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