PHARMACEUTICAL COMPOSITION COMPRISING GRANULAR PANTOPRAZOLE

摘要

Pharmaceutical composition comprising pantoprazole as the active ingredient. The pantoprazole is present in the form of particles having an average particle size within the range of 60 [mu]m to 250 [mu]m. Pantoprazole having an average particle size within the range of 60 [mu]m to 250 [mu]m is prepared by a process comprising the steps of wetting pantoprazole with water having a pH of 10 to 12 in a high shear mixer, passing the wet pantoprazole through a sieve having a mesh size of 0.8 to 2 mm, and drying the mass in a fluid bed dryer.