| 摘要 |
[Summary] [Problem] There is provided a bioequivalence evaluation method not only of evaluating bioequivalence between an original drug and a corresponding generic drug but also of enabling to compare bioequivalence between generic drugs. [Means of Solving the Problem] The bioequivalence between generic drugs is evaluated according to the Expression (1) wherein CCVCmax g stands for the calibration coefficient of variation of Cmax (the maximum blood concentration), CCVTmax g stands for the calibration coefficient of variation of Tmax (the time to maximum blood concentration), CCVT1/2 g stands for the calibration coefficient of variation of the half-life (T1/2), and CCVAUC g stands for the calibration coefficient of variation of AUC (the blood concentration-area under the curve).
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