发明名称 |
COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING PYRIDAZINE SULFONAMIDE DERIVATIVES |
摘要 |
<p>The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-3 or encompassed by formula I-III) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.</p> |
申请公布号 |
WO2010123822(A1) |
申请公布日期 |
2010.10.28 |
申请号 |
WO2010US31608 |
申请日期 |
2010.04.19 |
申请人 |
INSTITUTE FOR ONEWORLD HEALTH;PENROSE, STEPHEN DAVID;DOYLE, KEVIN JAMES |
发明人 |
PENROSE, STEPHEN DAVID;DOYLE, KEVIN JAMES |
分类号 |
A01N43/58;A61K31/50 |
主分类号 |
A01N43/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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