发明名称 ANTICANCER TOCOPHERYL SUCCINATE DERIVATIVES
摘要 Compounds of formula I: wherein X is selected from oxygen, nitrogen and sulfur; n is 0 or 1; R1 is selected from alkyl, carboxylic acid, carboxylate, carboxamide, ester and combinations thereof; R2 is selected from alkyl, substituted alkyl, carboxylic acid, carboxylate, carboxamide, sulfonyl, sulfonamide and combinations thereof; and derivatives and metabolites thereof. Further provided are methods of using a compound of formula I to prevent and/or treat a subject having a condition characterized by unwanted cell proliferation. Also provided are pharmaceutical compounds comprising one or more compounds of formula I, or derivatives or pharmaceutically acceptable salts thereof.
申请公布号 US2010273871(A1) 申请公布日期 2010.10.28
申请号 US20100768392 申请日期 2010.04.27
申请人 THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION 发明人 CHEN CHING-SHIH;WANG DASHENG
分类号 A61K31/355;A61P35/00;C07D311/72 主分类号 A61K31/355
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