HUMAN ANTI-AMYLOID BETA PEPTIDE ANTIBODY AND FRAGMENT OF SAID ANTIBODY

摘要

A human anti-amyloid &bgr; peptide (hereinafter referred to as “A&bgr;”) antibody that binds to A&bgr; to thereby inhibit aggregation of A&bgr; molecules, and a fragment of said antibody are provided. The antibody and a fragment thereof according to the present invention, comprising a variable region of a human-derived anti-A&bgr; antibody, strongly reacts with A&bgr; to thereby inhibit its aggregation and hence may be used as a medicament for the prophylaxis and treatment of Alzheimer dementia.