CRYSTAL FORM A OF FURANODIENE, THE PREPARATION METHOD AND THE USEFUL FOR PREPARING THE ANTITUMOR DRUG THEREOF

摘要

The crystal form A of furanodiene which characteristic peaks at 2? of 11.4°(±0.1°), 13.4°(±0.1°), 15.3°(±0.1°), 19.6°(±0.1°) and 24.6°(±0.1°) in x-ray powder diffraction pattern. This crystal has the absorption peak at 69? in differential scanning calorimetry pattern. The preparation method of the crystal form A of furanodiene. The method of treating tumor by using the crystal form A of furanodiene. The crystal form A of furanodiene can improve the pharmacokinetics activity of the furanodiene and strengthen the drugability of the furanodiene. The present method overcomes the problem in the traditional method which uses the supercritical carbon dioxide extraction to obtain the furanodiene, such as the complex process and the expensive cost.