发明名称 |
HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE |
摘要 |
<p>The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: -n and m denote, independently of one another, an integer ranging from 1 to 4,—X denotes an oxygen atom or an N—R3 group,—R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and—R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.</p> |
申请公布号 |
EP2240501(A1) |
申请公布日期 |
2010.10.20 |
申请号 |
EP20090700113 |
申请日期 |
2009.01.05 |
申请人 |
UNIVERSITE DE NANTES;CHU NANTES;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
EGOROV, MAXIM;FORTUN, YANNICK;HEYMANN, DOMINIQUE;LEBRETON, JACQUES;MATHE, MONIQUE;PADRINES, MARC;REDINI, FRANCOISE |
分类号 |
C07F9/38;A61K31/663;A61P3/14;A61P19/10;A61P35/00 |
主分类号 |
C07F9/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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