发明名称 HYDROXY-BISPHOSPHONIC ACID DERIVATIVES AS VECTOR FOR TARGETING BONE TISSUE
摘要 <p>The present invention relates to hydroxy-bisphosphonic acid derivatives corresponding to general formula (I): in which: -n and m denote, independently of one another, an integer ranging from 1 to 4,—X denotes an oxygen atom or an N—R3 group,—R1 and R3 denote, independently of one another, a linear or branched C1 to C6 alkyl group, and—R2 denotes a residue of a molecule of therapeutic or diagnostic interest, or pharmaceutically acceptable salts of said derivatives, and also the method for the preparation thereof and the therapeutic or diagnostic use thereof.</p>
申请公布号 EP2240501(A1) 申请公布日期 2010.10.20
申请号 EP20090700113 申请日期 2009.01.05
申请人 UNIVERSITE DE NANTES;CHU NANTES;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 发明人 EGOROV, MAXIM;FORTUN, YANNICK;HEYMANN, DOMINIQUE;LEBRETON, JACQUES;MATHE, MONIQUE;PADRINES, MARC;REDINI, FRANCOISE
分类号 C07F9/38;A61K31/663;A61P3/14;A61P19/10;A61P35/00 主分类号 C07F9/38
代理机构 代理人
主权项
地址