| 发明名称 |
IDENTIFICATION OF HUMAN CELL LINES FOR THE PRODUCTION OF HUMAN PROTEINS BY ENDOGENOUS GENE ACTIVATION |
| 摘要 |
The invention relates to methods for the selection of human cells for the preparation of human proteins by endogenic gene activation in order to produce human proteins in economical yields and in a form which is suitable for the production of a pharmaceutical preparation. The invention furthermore relates to a method for the production of human proteins in a cell line identified in this manner.
|
| 申请公布号 |
CA2298412(C) |
申请公布日期 |
2010.10.19 |
| 申请号 |
CA19982298412 |
申请日期 |
1998.07.22 |
| 申请人 |
ROCHE DIAGNOSTICS GMBH |
发明人 |
BRANDT, MICHAEL;FRANZE, REINHARD;PESSARA, ULRICH |
| 分类号 |
C12N15/09;C12N15/12;A61K38/00;C07K14/505;C12N5/10;C12N15/10;C12N15/62;C12N15/63;C12N15/85 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
