USE OF IMPROVED TOLUIDINE BLUE IN PHOTODYNAMIC THERAPY

摘要

A method of treating oral cancer is provided. The method comprises the steps of providing at least one photodynamic treatment comprising the steps of (i) applying a composition comprising improved toluidine blue to oral cells; wherein the composition comprises a greater percentage by weight of the conformational isomers of toluidine blue compared to the N-demethylated derivatives thereof; and wherein the composition localizes to oral cancer cells,- and activating the applied composition, thereby killing the oral cancer cells.