发明名称 |
Cancer Therapy |
摘要 |
The present application relates to compositions and methods for treating a proliferative disorder by administering to a subject a pharmaceutical composition of a dual kinase inhibitor. Catecholic butanes cane serve as dual kinase inhibitors for purposes of methods described herein. Subjects can be further treated by co-administering an EGFR inhibitor. The present application also relates to analyzing a sample with respect to levels of IGF-1R and EGFR and comparing levels of IGF-1R and EGFR to a control. Patients can be selected for treatment with a catecholic butane based on the assessment; optionally, patients can be further treated with an EGFR inhibitor, an IGF-1R inhibitor, or both.
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申请公布号 |
US2010256232(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
US20090614283 |
申请日期 |
2009.11.06 |
申请人 |
TRIACT THERAPEUTICS, INC. |
发明人 |
WHITE THOMAS F.;SCHNIPPER EDWARD F.;HOTH DAN |
分类号 |
A61K31/225;A61K31/05;A61K31/09;A61P35/00 |
主分类号 |
A61K31/225 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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