| 摘要 |
A device for injecting materials for intervertebral fusions, kits containing the device, injectable and implantable modified poly(methyl methacrylate) (mPMMA) materials, and methods of use thereof, particularly in interverterbral fusions or intravertebral structural fortification, are described herein. The device contains an outer canula (20), an inner canula (30) that is in telescoping relation with respect to the outer canula (20) and removable therefrom, and one or more barrier forming materials, preferably two balloons. When the mPMMA material is cured, it produces a cement with a sufficient porosity to allow for bone growth through the cement to connect one vertebral endplate to the adjacent endplate. The mPMMA cement has sufficient compressive strength to withstand physiologic loads of the body during weight bearing activity and exhibits a Young's modulus of elasticity which is slightly less than cortical bone. Additionally, the mPMMA is able to bind to calcium phosphate and/or BMP. |
