ELECTROCHEMICAL PATTERNING AND DISSOLUTION OF POLYELECTROLYTE MULTILAYERS

摘要

Described is an electric potential driven drug delivery system, which drug delivery system is suitable for the time dependent dispensing of at least one active ingredient. Said drug delivery system comprises at least one active ingredient, a substrate with at least a semi-conductive part, wherein at least said semi-conductive part is covered by at least one bilayer of oppositely charged monolayers. Said at least one active ingredient may form one of said monolayers, or said at least one active may be incorporated within one of the monolayers, or said active ingredient may form a layer that is placed between said two oppositely charged monolayers. For use, said multilayers covered substrate is connected to a regulating means that is suitable to change the potential of said substrate such that one or more of said monolayers - and therewith the active ingredient therein - are released.