The present invention provides methods of obtaining structural information about a biopolymer sample. The methods include labeling portions of a biopolymer, such as DNA or RNA, linearizing the biopolymer in some cases, and determining the distance between the labels. The user can then compare different samples' between-label distances to qualitatively compare different samples and to assay a given sample for additions or deletions of nucleotides in the regions flanked by the labels. The methods also permit sequencing of biopolymers.
申请公布号
WO2010059731(A3)
申请公布日期
2010.10.07
申请号
WO2009US64996
申请日期
2009.11.18
申请人
BIONANOMATRIX, INC.;XIAO, MING;CAO, HAN;DESHPANDE, PARIKSHIT, A.;BOYCE-JACINO, MICHAEL
发明人
XIAO, MING;CAO, HAN;DESHPANDE, PARIKSHIT, A.;BOYCE-JACINO, MICHAEL