A METHOD FOR TREATING RHEUMATOID ARTHRITIS WITH B-CELL ANTAGONISTS

摘要

A method of treating rheumatoid arthritis in a patient is disclosed which comprises administering an effective amount of a B-cell antagaonist to the patient to treat the rheumatoid arthritis, provided that the rheumatoid arthritis is characterized by an elevated level of a positive acute phase protein and an elevated titer of a rheumatoid arthritis-associated autoantibody in a sample from the patient. Further provided are kits and articles of manufacture useful for such methods.