发明名称 |
A PEG-ALBUMIN COMPOSITION HAVING AT LEAST ONE PROTECTED THIOL REGION AS A PLATFORM FOR MEDICATIONS |
摘要 |
This composition comprises a polyethylene glycol-albumin composition having at least one protected thiol region wherein the composition comprises PEG-AlbCys34 with Cys-34 preserved as a thiol. The albumin is linked to medications such as, antioxidants with a reduced sulfhydryl group through the Cys 34 residing on the albumin. The compositions are useful in treating patients.
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申请公布号 |
CA2754395(A1) |
申请公布日期 |
2010.10.07 |
申请号 |
CA20102754395 |
申请日期 |
2010.04.02 |
申请人 |
THE UNIVERSITY OF TOLEDO |
发明人 |
ASSALY, RAGHEB;DIGMAN, JOHN DAVID;SHAPIRO, JOSEPH I. |
分类号 |
A01N37/18;A61K38/00 |
主分类号 |
A01N37/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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