METHOD FOR PREPARING ACYCLOVIR 2/3 HYDRATE

摘要

Preparation of acyclovir 2/3 hydrate comprises adding acyclovir into water at weight ratio of 1:5-50, dissolving at 50-100?, filtering, cooling filtrate at 0-30? to separate crystal, filtering filtrate, collecting crystal, and drying crystal at 0-150? for 0.5-24 hours to obtain acyclovir 2/3 hydrate. The preparation process is simple and suitable for industrial production. The prepared product has good and stable crystal form.