摘要 |
<p>The invention relates to the use of endogenous metabolites to produce a metabolic profile of a disorder or disease in a subject, e.g. an autoimmune disease, in particular rheumatoid arthritis, and the analysis of such metabolic profiles in order to find disturbances in such profiles in a subject which are caused by or correlated with the said diseases or disorders. Such disturbances can be normalised by treatment of the subject with specified compounds, particularly N-(2-chloro-3,4-dimethoxybenzylideneamino) guanidine or an aminoguanidine.</p> |
申请人 |
ANAMAR AB;LUNDSTEDT, ERIK, TORBJOERN;TRYGG, NILS, JOHAN;GABRIELSSON, JON, ROBERT;EKSTROEM, GUNILLA;WEBBER, PHILIP, MICHAEL |
发明人 |
LUNDSTEDT, ERIK, TORBJOERN;TRYGG, NILS, JOHAN;GABRIELSSON, JON, ROBERT;EKSTROEM, GUNILLA |