发明名称 Matrix metalloproteinase inhibitors
摘要 Disclosed is a beta hydroxy acid of formula (I) or physiologically functional derivative thereof selected from pharmaceutically acceptable esters, amides and carbamates, salts and solvates thereof wherein R1, R1' and R3 are all hydrogen, ABD is CH2-CH2, R2 is COOH, X is methylene, Y is CH(OH), Z is a bond and the other substituents are defined in the specification. Also disclosed is a composition comprising said acid, a process of preparation of said acid and a use of acid of formula (I) for the manufacture of a medicament for the treatment of inflammatory conditions or autoimmune disorders. (62) Divided Out of 545211
申请公布号 NZ573479(A) 申请公布日期 2010.09.30
申请号 NZ20040573479 申请日期 2004.09.10
申请人 GLAXO GROUP LIMITED 发明人 GAINES, SIMON;HOLMES, IAN PETER;MARTIN, STEPHEN LEWIS;WATSON, STEPHEN PAUL
分类号 C07D405/10;A61K31/4035;A61K31/505;A61K31/506;A61P29/00;C07D209/48;C07D239/54;C07D403/10 主分类号 C07D405/10
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