发明名称 |
NEURONAL VIABILITY FACTOR AND USE THEREOF |
摘要 |
The present disclosure concerns a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a compound selected in the group comprising (i) a polypeptide comprising an amino acid sequence selected in the group comprising the amino acid sequence of the long isoform in Homo sapiens of the RdCVF2 gene (SEQ ID NO:10), orthologs, derivatives and fragments thereof, (ii) a polynucleotide coding for said polypeptide, (iii) a vector comprising said polynucleotide, and (iv) a host cell genetically engineered expressing said polypeptide; the use of such a composition for the manufacture of a medicament for treating and/or preventing a neurodegenerative disorder in a subject; and a method of testing a subject thought to have or be predisposed to having a neurodegenerative disorder.
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申请公布号 |
US2010247496(A1) |
申请公布日期 |
2010.09.30 |
申请号 |
US20080602736 |
申请日期 |
2008.06.05 |
申请人 |
INSTITUTE NATIONAL DE LA SANTE ET DE LAS RECHERCHE MEDICALE (INSERM) |
发明人 |
LEVEILLARD THIERRY;SAHEL JOSE-ALAIN;JAILLARD CELINE;POCH OLIVIER |
分类号 |
A61K35/12;A61K38/12;A61P25/00;A61P25/16;A61P25/28 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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