METHODS FOR DETERMINING THE LIKELIHOOD OF A PATIENT CONTRACTING A NOSOCOMIAL INFECTION AND FOR DETERMINING THE PROGNOSIS OF THE COURSE OF A SEPTIC SYNDROME
摘要
<p>The present invention relates to a method for determining the likelihood of a patient contracting a nosocomial infection and to a method for determining the prognosis of the course of a septic syndrome in a patient, according to which: a. a biological sample is obtained from the patient and biological material is extracted from the biological sample; b. at least one specific reagent is obtained from an expression construct of at least one target gene selected from target genes S100A9 and S100A8; c. the expression of at least one of the target genes S100A9 and S100A8 is determined, an overexpression relative to a predetermined threshold value indicating the likelihood of contracting a nosocomial infection as well as indicating a poor prognosis of the course of a septic syndrome.</p>
申请公布号
WO2010082004(A9)
申请公布日期
2010.09.30
申请号
WO2010FR50070
申请日期
2010.01.18
申请人
BIOMERIEUX;HOSPICES CIVILS DE LYON;CAZALIS, MARIE-ANGELIQUE;LEPAPE, ALAIN;MONNERET, GUILLAUME;MOUGIN, BRUNO;PACHOT, ALEXANDRE