发明名称 POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS AND ANTAGONISTS
摘要 The invention relates to anti-VEGF polypeptides and antibody single variable domains (dAbs) that are resistant to degradation by a protease, as well as antagonists comprising these. The polypeptides, dAbs and antagonists are useful for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient, as well as for treating cancer and inflammatory disease, such as arthritis.
申请公布号 US2010247515(A1) 申请公布日期 2010.09.30
申请号 US20080663506 申请日期 2008.06.04
申请人 DOMANTIS LIMITED 发明人 STEWARD MICHAEL;PUPECKA MALGORZATA;TOMLINSON IAN;ENEVER CAROLYN;JESPERS LAURENT S.;BATUWANGALA THIL DINUK
分类号 A61K39/395;A61P1/00;A61P1/06;A61P35/00;C07K16/18 主分类号 A61K39/395
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