COMPOSITIONS OF MESENCHYMAL STEM CELLS TO REGENERATE BONE
摘要
The present invention encompasses an osteogenic composition comprising mesenchymal stem cells pre-cultured in the presence of an agent that accelerates canonical Wnt signaling therein. Also, provided are osteogenic compositions incorporated into a biocompatible gel. The present invention provides methods for treating bone degeneration or injury associated with a pathophysiological condition in a mammal or for accelerating repair of a skeletal injury in a mammal by administering to the mammal or contacting the site of injury with the osteogenic composition.
申请公布号
WO2010111278(A1)
申请公布日期
2010.09.30
申请号
WO2010US28332
申请日期
2010.03.23
申请人
THE TEXAS A&M UNIVERSITY SYSTEM;GREGORY, CARL, A.;PROCKOP, DARWIN, J.