发明名称 Aza spiro alkane derivatives as inhibitors of metalloproteases
摘要 The present invention provides a compound of Formula (I) or Formula (II): enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula (I) and (II) are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
申请公布号 AU2010214762(A1) 申请公布日期 2010.09.23
申请号 AU20100214762 申请日期 2010.09.01
申请人 INCYTE CORPORATION 发明人 BRIAN METCALF;FENGLEI ZHANG;JINCONG ZHOU;MEIZHONG XU;WENQING YAO
分类号 C07D401/02;A61K;A61K31/4188;A61K31/424;A61K31/428;A61K31/4747;A61K31/495;C07D;C07D471/10;C07D491/10;C07D497/10 主分类号 C07D401/02
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