发明名称 |
SUSTAINED RELEASE OF MICROCRYSTALLINE PEPTIDE SUSPENSIONS |
摘要 |
The invention relates to a fluid, milky microcrystalline aqueous suspension of a peptide or peptidomimetic and a counter-ion of a strong proton donor in water, wherein the peptide or peptidomimetic and counter-ion are present in amounts and at a molar ratio sufficient to form the suspension upon mixing and without formation of a gel. The invention also relates to lyophilized compositions that include a dried suspension, methods of making the lyophilized composition, methods of preparing the suspension, and sustained release formulations prepared by the methods.
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申请公布号 |
US2010239683(A1) |
申请公布日期 |
2010.09.23 |
申请号 |
US20100795246 |
申请日期 |
2010.06.07 |
申请人 |
ARDANA BIOSCIENCE LIMITED |
发明人 |
DEGHENGHI ROMANO;BOUTIGNON FRANCOIS |
分类号 |
A61K9/10;A61K9/19;A61K9/00;A61K9/14;A61K9/22;A61K38/02;A61K38/04;A61K38/09;A61K38/24;A61K38/31;A61K47/02;A61K47/10;A61K47/12;A61K47/20;A61K47/26;A61P5/02;A61P5/04;A61P43/00 |
主分类号 |
A61K9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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