发明名称 |
SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREOF |
摘要 |
The present invention relates to novel adenovirus strains with an improved seroprevalence. In one aspect, the present invention relates to isolated polypeptides of adenoviral capsid proteins such as hexon, penton and fiber protein and fragments thereof and polynucleotides encoding the same. Also provided is a vector comprising the isolated polynucleotide according to the invention and adenoviruses comprising the isolated polynucleotides or polypeptides according to the invention and a pharmaceutical composition comprising said vector, adenovirus, polypeptide and/or polynucleotide. The invention also relates to the use of the isolated polynucleotides, the isolated polypeptides, the vector, the adenoviruses and/or the pharmaceutical composition for the therapy or prophylaxis of a disease. |
申请公布号 |
WO2010086189(A3) |
申请公布日期 |
2010.09.23 |
申请号 |
WO2010EP00616 |
申请日期 |
2010.02.02 |
申请人 |
OKAIROS AG, SWITZERLAND;COLLOCA, STEFANO;NICOSIA, ALFREDO;CORTESE, RICCARDO;AMMENDOLA, VIRGINIA;AMBROSIO, MARIA |
发明人 |
COLLOCA, STEFANO;NICOSIA, ALFREDO;CORTESE, RICCARDO;AMMENDOLA, VIRGINIA;AMBROSIO, MARIA |
分类号 |
C07K14/075;A61K39/00;A61K48/00;C12N7/00;C12N15/861 |
主分类号 |
C07K14/075 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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