发明名称 |
MULTIVALENT, DRYING RESISTANT, EVOLUTION-BASED VACCINES |
摘要 |
Disclosed is a recombinant nonpermutated bacteriophage that includes a nucleic acid sequence that is at least 150 kb in length wherein the bacteriophage is made to display one or more surface antigens such as heterologous polypeptides, and compositions and kits that include the recominant nonpermutated bacteriophages of the present invention. Also disclosed are methods of inducing an immune response in a subject that involve administration of a pharmaceutically effective amount of a composition comprising the recombinant nonpermutated bacteriophages of the present invention. |
申请公布号 |
WO2010062837(A3) |
申请公布日期 |
2010.09.23 |
申请号 |
WO2009US65362 |
申请日期 |
2009.11.20 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;SERWER, PHILIP;KOHLI, GURNEET |
发明人 |
SERWER, PHILIP;KOHLI, GURNEET |
分类号 |
C12N7/00 |
主分类号 |
C12N7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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