摘要 |
Disclosed is a compound represented by Formula (I): or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the compound of Formula (I) or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof and methods of inhibiting 11beta-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Values for the variables in Formula (I) are defined herein. |
申请人 |
VITAE PHARMACEUTICALS, INC. |
发明人 |
CLAREMON, DAVID, A.;ZHUANG, LINGHANG;TICE, COLIN, M.;YE, YUANJIE;HE, WEI;SINGH, SURESH, B.;XU, ZHENRONG;CACATIAN, SALVACION;ZHAO, WEI |