发明名称 CYCLIC UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1
摘要 Disclosed is a compound represented by Formula (I): or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the compound of Formula (I) or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof and methods of inhibiting 11beta-HSD1 activity comprising the step of administering to a mammal in need of such treatment an effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Values for the variables in Formula (I) are defined herein.
申请公布号 EP2229368(A1) 申请公布日期 2010.09.22
申请号 EP20080859146 申请日期 2008.12.10
申请人 VITAE PHARMACEUTICALS, INC. 发明人 CLAREMON, DAVID, A.;ZHUANG, LINGHANG;TICE, COLIN, M.;YE, YUANJIE;HE, WEI;SINGH, SURESH, B.;XU, ZHENRONG;CACATIAN, SALVACION;ZHAO, WEI
分类号 C07D239/10;A61K31/513;A61K31/535;A61P3/00;A61P9/10;C07D239/42;C07D265/10;C07D401/12;C07D413/12 主分类号 C07D239/10
代理机构 代理人
主权项
地址