发明名称 |
Riluzole aqueous suspensions |
摘要 |
Physically and chemically stable aqueous suspensions of riluzole are disclosed together with the manufacturing methods thereof. Such aqueous suspensions comprise riluzole in particle form and at least a wetting agent, preferably a surfactant. Riluzole is in amounts from about 0.1 % to about 20% w/v and has an average particle size lower than 200 µm; such suspensions are devoided of the known local (mouth) anaesthetic effects of riluzole.
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申请公布号 |
EP2228054(A1) |
申请公布日期 |
2010.09.15 |
申请号 |
EP20090425101 |
申请日期 |
2009.03.13 |
申请人 |
ITALFARMACO S.P.A. |
发明人 |
ADAMI, MARCO;ARTICO, ROBERTA;BARBARESCHI, DANIELE;MOSCOSO, JAIME;OLDONI, TIZIANO;MASCAGNI, PAOLO |
分类号 |
A61K9/00;A61K31/428;A61K47/20;A61K47/34;A61P25/28 |
主分类号 |
A61K9/00 |
代理机构 |
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