发明名称 |
ALGINATE BIOMATERIALS FOR THE TREATMENT OF HEPATIC DISORDERS |
摘要 |
The present invention relates to methods for the treatment of hepatic disorders in a subject in need thereof. More specifically, the methods of the invention are based on the administration, preferably, systemic administration, of a therapeutically effective amount of at least one biocompatible alginate biomaterial, any modification thereof and any combination thereof. The invention further provides methods for sustaining serum albumin levels, and/or reducing serum AST and ALT, in subjects suffering from hepatic disorder. Still further, the invention provides methods for reducing apoptosis and inducing cell proliferation in a damaged liver tissue of a subject suffering of hepatic disorder, using the alginate biomaterial described by the invention. |
申请公布号 |
EP2227237(A1) |
申请公布日期 |
2010.09.15 |
申请号 |
EP20080853658 |
申请日期 |
2008.11.27 |
申请人 |
HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD.;BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY |
发明人 |
ILAN, YARON;LALAZAR, GADI;SHTEYER, EYAL;BEN-YAAKOV, AMI;COHEN, SMADAR;ELKAYAM, TSIONA |
分类号 |
A61K31/734;A61K31/738;A61L27/20;A61L31/04;A61P1/16 |
主分类号 |
A61K31/734 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|