发明名称 |
Methods for the early diagnosis of ovarian cancer |
摘要 |
The present invention discloses the protease hepsin is specifically over-expressed in ovarian and other malignancies. A number of hepsin peptides can induce immune responses to hepsin, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies. There is also provided a hepsin protein variant that is useful as a marker for ovarian cancer cells, prostate cancer cells or kidney cancer cells.
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申请公布号 |
US7795211(B2) |
申请公布日期 |
2010.09.14 |
申请号 |
US20030652993 |
申请日期 |
2003.08.29 |
申请人 |
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS |
发明人 |
O'BRIEN TIMOTHY J.;CANNON MARTIN J.;SANTIN ALESSANDRO;BEARD JOHN;SHIGEMASA KAZUSHI |
分类号 |
G01N33/574;A61K39/00;C07K14/435;C12Q1/37;C12Q1/68;G01N33/573 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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