发明名称 |
RNA Antagonist Compounds for the Inhibition of Apo-B100 Expression |
摘要 |
Short oligonucleotides directed against the Apo-B100 gene are provided for modulating the expression of Apo-B100. Methods of using these compounds for modulation of Apo-B100 expression and for the treatment of diseases associated with Apo-B100 expression are provided. The oligonucleotides comprise deoxyribonucleosides and locked nucleic acids.
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申请公布号 |
US2010227914(A1) |
申请公布日期 |
2010.09.09 |
申请号 |
US20080532275 |
申请日期 |
2008.03.19 |
申请人 |
SANTARIS PHARMA A/S |
发明人 |
HANSEN HENRIK FRYDENLUND;HANSEN JENS BO RODE;ROSENBOHM CHRISTOPH;STRAARUP ELLEN MARIE |
分类号 |
A61K31/7105;A61P9/10;C07H21/04;C12N15/113 |
主分类号 |
A61K31/7105 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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