发明名称 |
Chemical Switches for Detecting Reactive Chemical Agents |
摘要 |
Certain embodiments of the present invention relate to the preparation of microbeads that exhibit a “turn on” fluorescence response within seconds of exposure to an analyte vapor (e.g., a chemical warfare agent or a reactive stimulant). This sensing approach is modeled after the mechanism for inhibition of acetylcholinesterase enzyme activity, and utilizes a specific and irreversible reaction between phosphonyl halides and a fluorescent indicator. The present invention also relates to a sensor and a method for sensing an analyte through detection of changes in the fluorescing properties of the inventive microbeads.
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申请公布号 |
US2010227766(A1) |
申请公布日期 |
2010.09.09 |
申请号 |
US20070279899 |
申请日期 |
2007.02.22 |
申请人 |
TRUSTEES OF TUFTS COLLEGE |
发明人 |
WALT DANIEL R.;BENCIC-NAGALE SANDRA |
分类号 |
C40B30/00;C07D311/82;C40B40/04 |
主分类号 |
C40B30/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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