发明名称 |
Inhibitors of akt activtiy |
摘要 |
The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
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申请公布号 |
US2010222321(A1) |
申请公布日期 |
2010.09.02 |
申请号 |
US20060921352 |
申请日期 |
2006.06.07 |
申请人 |
ARMSTRONG DONNA J;HU ESSA H;KELLY III MICHAEL J;LAYTON MARK E;LI YIWEI;LIANG JUN;RODZINAK KEVIN J;ROSSI MICHAEL A;SANDERSON PHILIP E;WANG JIABING |
发明人 |
ARMSTRONG DONNA J.;HU ESSA H.;KELLY, III MICHAEL J.;LAYTON MARK E.;LI YIWEI;LIANG JUN;RODZINAK KEVIN J.;ROSSI MICHAEL A.;SANDERSON PHILIP E.;WANG JIABING |
分类号 |
A61K31/4375;A61K31/4709;A61K31/496;A61K31/501;A61K31/506;A61K31/517;A61K31/519;A61K31/5377;A61P35/00;C07D471/14;C07D513/04 |
主分类号 |
A61K31/4375 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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