发明名称 MICROFLUIDIC CELL SORTER UTILIZING BROADBAND COHERENT ANTI-STOKES RAMAN SCATTERING
摘要 A microfluidic cell sorter has a microfluidic structure (500) with a sample input channel (1 1 0) leading into an observation region (214), two buffer channels (1 1 8) configured to hydrodynamically focus a sample target cell (208) within the observation region, and at least two output channels (1 1 4). Apparatus directs the target cell into a selected output channel based on a cell sorting control signal (61 6). A CARS pulse source (524) generates CARS pulses (526), which are directed to the target cell within the observation region. A detector (530) detects CARS illumination scattered from the target signal and generates a spectrum signal based on the detected illumination. A processor (61 4) identifies the target cell based on the spectrum signal and generates the cell sorting control signal based on the identity of the target cell.
申请公布号 WO2010053796(A3) 申请公布日期 2010.09.02
申请号 WO2009US62419 申请日期 2009.10.28
申请人 THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODYCORPORATE;LEI, TIM, CHIFONG;GIBSON, EMILY, ABBOTT 发明人 LEI, TIM, CHIFONG;GIBSON, EMILY, ABBOTT
分类号 C12Q1/24;C12M1/34;G01N33/48 主分类号 C12Q1/24
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