MATERIALS AND METHODS FOR IDENTIFYING AND USING YEAST STRAINS THAT METABOLIZE PENTOSE SUGARS IN THE PRESENCE OF D-GLUCOSE
摘要
Disclosed herein are materials and methods for creating and/or isolating variants of yeasts especially variants of Saccharomyces cerevisiae that can grow on sugars other than D-glucose in the presence of amounts of 2-deoxy-glucose and or D- glucose that inhibit most strains of yeast from growing on sugars other than D- glucose. Selection media that can be used to isolate such variants include pentose sugars such as D-xylose, L-glutamine and 2-deoxy-glucose. Mutations in the Grr1 and Red genes in some strains also produce variants that can grow on sugars including the pentose D-xylose in the presence of 2-deoxy-glucose.
申请公布号
WO2010099343(A1)
申请公布日期
2010.09.02
申请号
WO2010US25448
申请日期
2010.02.25
申请人
INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION;GOEBL, MARK;WOODS, CARY;COCKLIN, ROSS;HEYEN, JOSH