CHIMERIC ALPHA Q-GUSTDUCIN G PROTEIN

摘要

PROBLEM TO BE SOLVED: To provide a method for screening a modulator of a bitter taste, sweet taste and palatable taste responses in a human.

SOLUTION: The Gαq-gustducinchimera G protein functionally conjugating with a G protein-conjugating type receptor is provided. The above chimera can be expressed in heterologous expression systems, and can be used as the basis of assays for identifying the modulators of gastatory receptors, especially the receptor of the bitter taste, sweet taste or palatable taste.

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