| 发明名称 |
AZIRIDINYL-EPOTHILONE COMPOUNDS |
| 摘要 |
Disclosed are aziridinyl epothilone compounds having Formula (X) and pharmaceutically acceptable salts and solvates thereof, wherein K is -O-, -S- or -NR7- and the remaining substituents are as defined in the specification. The compounds can be used in cancer treatment of for the preparation of conjugates for targeted drug delivery, especially folates.
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| 申请公布号 |
NZ572763(A) |
申请公布日期 |
2010.08.27 |
| 申请号 |
NZ20070572763 |
申请日期 |
2007.05.25 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
KIM, SOONG-HOON;VITE, GREGORY D;LEAMON, CHRISTOPHER P;VLAHOV, IONTCHO R |
| 分类号 |
C07D491/04;A61K31/396;A61K31/427;A61P35/00 |
主分类号 |
C07D491/04 |
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