PHARMACEUTICAL COMPOSITION FOR SUPPRESSING DNA METHYLTRANSFERASE, CONTAINING ARYLOXYACETYL-BASED COMPOUNDS AS ACTIVE INGREDIENTS,申请号WO2009KR06643-传众专利搜索

首页产品黄页商标征信

会员服务注册登录

法人/股东/高管

发明名称	PHARMACEUTICAL COMPOSITION FOR SUPPRESSING DNA METHYLTRANSFERASE, CONTAINING ARYLOXYACETYL-BASED COMPOUNDS AS ACTIVE INGREDIENTS
摘要	The present invention relates to a pharmaceutical composition for suppressing DNA methyltransferase, containing the aryloxyacetyl-based compounds expressed in chemical formula 1 as active ingredients. The composition of the present invention can be used as a therapeutic agent for tumors, neurological brain diseases, hematologic diseases, and epigenetic diseases caused by DNA hypermethylation. Further, the present invention provides uses of aryloxyacetyl-based compounds expressed in chemical formula (1) mentioned below or pharmaceutically acceptable salts thereof to produce a DNA methyltransferase inhibitor or a DNA methylation inhibitor. The present invention provides a method for treating diseases caused by DNA hypermethylation by administering aryloxyacetyl-based compounds (LW6) expressed in chemical formula 1, or pharmaceutically acceptable salts thereof, to mammals (including humans) that require DNA methytransferase inhibition or DNA methylation inhibition.
申请公布号	WO2010056048(A3)	申请公布日期	2010.08.26
申请号	WO2009KR06643	申请日期	2009.11.12
申请人	KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY;LEE, KYEONG;WON, MISUN;LEE, JUNG JOON;CHUNG, KYUNG-SOOK;PARK, SONG-KYU;KWON, BYOUNG-MOG;YIM, NAM-HUI;KANG, JUNG EUN;JIN, YINGLAN;XIA, YAN;KIM, BO YEON;AHN, JONG SEOG	发明人	LEE, KYEONG;WON, MISUN;LEE, JUNG JOON;CHUNG, KYUNG-SOOK;PARK, SONG-KYU;KWON, BYOUNG-MOG;YIM, NAM-HUI;KANG, JUNG EUN;JIN, YINGLAN;XIA, YAN;KIM, BO YEON;AHN, JONG SEOG
分类号	A61K31/166	主分类号	A61K31/166
代理机构		代理人
主权项
地址

您可能感兴趣的专利

POLYCYCLIC FUSED RING TYPE pi;-CONJUGATED ORGANIC MATERIALS, INTERMEDIATE THEREFOR, PROCESS FOR PRODUCING POLYCYCLIC FUSED RING TYPE pi;- CONJUGATED ORGANIC MATERIALS, AND PROCESS FOR PRODUCING INTERMEDIATE OF POLYCYCLIC FUSED RING TYPE pi;- CONJUGATED ORGANIC MATERIALS

METHOD AND SYSTEM FOR INTELLIGENT SEARCHING OF CRUDE OIL PROPERTIES AND KNOWLEDGE

Motor vehicle front seat occupant`s head position detecting system, has conducting plate connected to control circuit and two other plates connected to circuit which measures amplitude of sinusoidal voltage received on plates

Numeric message transmitting method for chip card, involves decrypting cryptogram obtained by encrypting message, using private key by executing multiplication,where message is encrypted and decrypted by modified kiayas and yung algorithm

Flat screen television e.g. plasma television, has front housing of size to receive variable size flat screen plasma display panels, where housing is fixed with decorative frame having groove and opening size corresponding to size of panel

Drawing instrument for e.g. tracing circle, has holes distributed at certain intervals with diameter of one millimeter, and rectangular, triangular and trapezoidal holes, lines and marks graduations, molded in mass of instrument

Preparation of middle distillates from paraffinic load produced by Fischer-Tropsch synthesis comprises use of hydrocracking/hydroisomerization catalyst comprising hydro-dehydrogenating element, oxides of silicon and non-zeolitic support

Motorized vehicle e.g. passenger car, theft preventing method, involves blocking use of radio frequency badge if test confirms that badge was lost, forgotten or stolen, and stopping or slowing down vehicle in absence of authorized badge

Internal combustion engine e.g. diesel engine, controlling method for vehicle, involves regulating temperature at input of particle filter by controlling fuel injection in cylinder and injection downstream of oxidation catalyst of engine

Internal combustion engine`s exhaust gas particle filtering and eliminating device for motor vehicle, has recuperating module with particle tanks coupled to particle-gas separation units to collect recuperated agglomerated particles

Optical component e.g. phase shift mask, forming method for microelectronic application, involves inserting adjustment layer between stack, etching stack and layer parts and annealing layer to contract it to less than one nanometer

Rooms separating partition for e.g. residence, has video screen, placed inside frame, comprising one face receiving image projected by video projector placed in one room and another face permitting visualization of image

Acetylene cylinder for use with oxygen cylinder, has thermal conducting device arranged outside body and is in thermal connection with interior of body in order to operate thermal exchange between device and interior of body

Trim strip for linking cab profile to accommodation module in motor caravan has increasing width from mid line toward roof line

Ophthalmic glass stamping device for ophthalmic glass machining laboratory, has actuator permitting to install one of stamping areas selectively on plate, and stamp made of compressible material to simultaneously install areas on glass

Dry-spray powder products for the protection of moulds for the centrifugal casting of iron pipes, in association with a wet-spray powder product

Windshield washer tank for motor vehicle, has cleaning fluid filler neck and pump connected to tubings, where tank is mounted in removable manner in rear corner of trough, of vehicle`s spare wheel, located under floor pan of boot of vehicle

Electricity and fluid distribution support`s arm for operation theatre, has braking device with one configuration where device brakes relative displacement between partial arms, and another configuration where arms are free in displacement

Wheel body structure for e.g. retractable skate, has wheel bodies provided to and made integrated with axial base and shares same outer diameter, and tire either injection or casting molded or directly mounted to wheel body

Pad for knee of e.g. elderly person, has spongy body formed of washable material and integrating adjustable straps surrounding knees so that body remains positioned between knees and fixed by straps, where body is surrounded by envelope