发明名称 Pyrazolopyrrolidines as inhibitors of gamma secretase
摘要 The invention provides compounds of Formula I wherein A, Y, R1, R1a, R2, and R2a are as described in the specification. Compounds of Formula I are useful in treating and/or preventing cognitive disorders, such as Alzheimer's disease. The invention also encompasses pharmaceutical compositions comprising compounds of Formula I, methods of preparing compounds of Formula I, and methods of treating cognitive disorders, such as Alzheimer's disease.
申请公布号 ZA200908919(B) 申请公布日期 2010.08.25
申请号 ZA20090008919 申请日期 2009.12.15
申请人 ELAN PHARMACEUTICALS INC. 发明人 DRESSEN, DARREN;BOWERS, SIMEON;GAROFALO, ALBERT W.;HOM, ROY K.;MATTSON, MATTHEW N.
分类号 A61K;A61P;C07D 主分类号 A61K
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