发明名称 CETP inhibitors
摘要 Compounds having the structure of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), B or R2 is a phenyl group which has an ortho amine or aminomethyl substituent which is further substituted, and the other of B or R2 is also a cyclic group.
申请公布号 US7781426(B2) 申请公布日期 2010.08.24
申请号 US20060087184 申请日期 2006.12.29
申请人 MERCK SHARP & DOHME CORP. 发明人 ALI AMJAD;LU ZHIJIAN;SINCLAIR PETER J.;TAYLOR GAYLE E.;THOMPSON CHRISTOPHER F.;SMITH CAMERON J.;DOWST ADRIAN A.;CHEN YI-HENG
分类号 A61K31/422;A61K31/443;A61K31/4525;A61K31/496;A61K31/5377;A61K31/541;A61K31/55;C07D401/02;C07D403/02;C07D413/02;C07D417/02 主分类号 A61K31/422
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