HEAT SHOCK PROTEIN 90 INHIBITORS, METHODS OF PREPARING SAME, AND METHODS FOR THEIR USE
摘要
Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and conditions, such as inflammation and neurodegenerative disorders. Methods of treating and preventing cancer and other Hsp90 related diseases and conditions are disclosed that include administering to the subject a therapeutically effective amount of an Hsp90 inhibitor. Methods of preparing the novel Hsp90 inhibitors are also provided.
申请公布号
WO2010042500(A3)
申请公布日期
2010.08.19
申请号
WO2009US59677
申请日期
2009.10.06
申请人
EMORY UNIVERSITY;MIN, JAEKI;DU, YUHONG;THEPCHATRI, PAHK;LIOTTA, DENNIS C.;FU, HAIAN
发明人
MIN, JAEKI;DU, YUHONG;THEPCHATRI, PAHK;LIOTTA, DENNIS C.;FU, HAIAN