TOPICAL FORMULATIONS COMPRISING ION CHANNEL MODULATORS

摘要

Disclosed herein are pharmaceutical formulations comprising particles of formula (1) : wherein R1, R2, R3, R4, R5, R6, n and * are each defined in specification. Also disclosed are methods of decreasing intraocular pressure comprising topically applying a benzopyranyl guanidine derivative of formula 1 to an eye.