发明名称 ANTI-PD-L1 ANTIBODIES AND THEIR USE TO ENHANCE T-CELL FUNCTION
摘要 The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity.
申请公布号 US2010203056(A1) 申请公布日期 2010.08.12
申请号 US20090633339 申请日期 2009.12.08
申请人 GENENTECH, INC. 发明人 IRVING BRYAN;CHIU HENRY;MAECKER HEATHER;MARIATHASAN SANJEEV;LEHAR SOPHIE M.;WU YAN;CHEUNG JEANNE
分类号 A61K39/395;A61K38/16;A61P31/12;A61P33/02;A61P35/00;C07H21/04;C07K16/00;C12N1/21;C12N5/10;C12N15/63;C12P21/06 主分类号 A61K39/395
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