发明名称 |
DERIVATIVES OF AZASPIRANYL-ALKYLCARBAMATES OF 5-MEMBER HETEROCYCLIC COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF |
摘要 |
The invention relates to a compound of the general formula (I) in which R2 is a hydrogen or fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6-alkoxy, NR8R9 group; m, n, o and p are independently an integer equal to 0, 1, 2 or 3; A is a covalent bond or a C1-8-alkylene group; R1 is an optionally substituted aryl or heteroaryl group; R3 is a hydrogen or fluorine atom or a C1-6-alkyl group or a trifluoromethyl group; R4 is an optionally substituted 5-member heterocyclic compound; the compound being in the form of a base or acid addition salt. The invention also relates to the therapeutic use thereof. |
申请公布号 |
WO2010089510(A2) |
申请公布日期 |
2010.08.12 |
申请号 |
WO2010FR50183 |
申请日期 |
2010.02.04 |
申请人 |
SANOFI-AVENTIS;ABOUABDELLAH, AHMED;CHEREZE, NATHALIE;FAYOL, AUDE;LOCHEAD, ALISTAIR;SAADY, MOURAD;VACHE, JULIEN;YAICHE, PHILIPPE |
发明人 |
ABOUABDELLAH, AHMED;CHEREZE, NATHALIE;FAYOL, AUDE;LOCHEAD, ALISTAIR;SAADY, MOURAD;VACHE, JULIEN;YAICHE, PHILIPPE |
分类号 |
C07D413/14;A61K31/438;A61K31/444;A61K31/4709;A61P1/00;A61P9/00;A61P25/00;A61P29/00;A61P31/00;A61P31/12;A61P35/00;A61P37/00;C07D205/12;C07D209/54;C07D213/74;C07D215/38;C07D221/20;C07D261/12;C07D277/24;C07D417/14 |
主分类号 |
C07D413/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|