发明名称 DERIVATIVES OF INDOLE 2-CARBOXAMIDES AND AZAINDOLE 2-CARBOXAMIDES SUBSTITUTED BY A SILANYLE GROUP, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF.
摘要 <p>The invention relates to compounds of the general formula (I) in which: G1, G2, G3 et G4 are independent from one another, a C-X group or a nitrogen atom; one of G1, G2, G3 and G4 and at most one of G1, G2, G3 and G4 is a C-X group In which X is a -Si(X1)(X2)(X3) group; n is 0, 1, 2 or 3; Y is an optionally substituted aryl or heteroaryl; Z1, Z2, Z3, Z4 are independent from one another, a nitrogen atom or a C(R6) group, at least one being a nitrogen atom and at least one being a C(R6) group; Z is cyclic amino or acyclic amino; said compounds can be in the state of a base or an addition salt to an acid, as well as in the hydrate or solvate state. The invention also relates to a method for preparing the same and to the therapeutic use thereof.</p>
申请公布号 MX2010008101(A) 申请公布日期 2010.08.04
申请号 MX20100008101 申请日期 2009.01.20
申请人 SANOFI-AVENTIS 发明人 LAURENT DUBOIS;YANNICK EVANNO;ANDRE MALANDA
分类号 C07D401/12;A61K31/4439;A61K31/695;A61P3/00;A61P13/00;A61P15/00;A61P25/00;C07D401/14;C07F7/08;C07F7/10;C07F7/12 主分类号 C07D401/12
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