发明名称 |
COMBINATION OF AN NMDA RECEPTOR ANTAGONIST AND A SELECTIVE SEROTONIN REUPTAKE INHIBITOR FOR THE TREATMENT OF DEPRESSION AND OTHER MOOD DISORDERS |
摘要 |
The present invention provides a method for the treatment of depression, including treatment-resistant depression, and other mood disorders using a combination of an NMDA receptor antagonist and a SSRI that is citalopram or escitalopram. It has unexpectedly been shown that the combination has a synergistic and potentiated effect of either compound as monotherapy, resulting in an enhanced therapeutic effect at lower doses.
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申请公布号 |
CA2528622(C) |
申请公布日期 |
2010.08.03 |
申请号 |
CA20042528622 |
申请日期 |
2004.05.27 |
申请人 |
FOREST LABORATORIES, INC. |
发明人 |
GUPTA, SANDEEP;SAMORISKI, GARY |
分类号 |
A61K31/13;A61K;A61K31/16;A61K31/343;A61K31/551;A61K45/06 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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